Discovering New Enzymes for Biosynthesis and Biocatalysis

　　报告题目：Discovering New Enzymes for Biosynthesis and Biocatalysis

　　报告人：唐奕 教授 (University of California Los Angeles)

　　报告时间：6月17日 上午9：00

　　报告地点：徐汇校区哲生馆1楼会议室

　　报告摘要：

　　Biosynthesis of structurally complex natural products requires the coordinated actions of many enzymes. Through the discovery and characterization of natural product biosynthetic pathways, many enzymes of novel structures and functions have been identified. In this talk, I will discuss some interesting examples from our recent work on both bacterial and fungal secondary metabolism. We will highlight studies on well-known (such as tetracycline and lovastatin) and newly discovered natural products. In addition, I will also present protein engineering efforts in which a biosynthetic enzyme was converted into a commercial biocatalyst for the semisynthesis of a blockbuster drug.